| Catalog Number | GTX108054 |
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| Product Name | Tapasin-related protein antibody |
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| Full Name | TAP binding protein-like |
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| Synonyms | TAPBPL|FLJ10143|TAPBP-R|TAPBPR|TAP binding protein-like |
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| Product Description | Rabbit polyclonal antibody to Tapasin-related protein (TAP binding protein-like) |
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| Background | Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 408 and 468 of Human Tapasin-related protein |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Application Note | Antibody reactive against peptide, detects immunogen. Further validation in progress. |
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| Positive Controls | Synthetic peptide: 1:8,000 |
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| Target | Tapasin-related protein |
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| Predicted Target Size(KDa) | 50 |
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| Cellular Localization | Cell membrane; Single-pass type I membrane protein (Probable) | Endoplasmic reticulum membrane; Single-pass type I membrane protein (Probable) | Microsome membrane; Single-pass type I membrane protein (Probable) |
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| Form Supplied | Liquid |
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| Concentration | 1 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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