| Catalog Number | GTX108143 |
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| Product Name | P2Y12 antibody |
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| Full Name | purinergic receptor P2Y, G-protein coupled, 12 |
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| Synonyms | P2RY12|ADPG-R|HORK3|P2T(AC)|P2Y(AC)|P2Y(ADP)|P2Y(cyc)|P2Y12|SP1999|purinergic receptor P2Y, G-protein coupled, 12 |
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| Product Description | Rabbit polyclonal antibody to P2Y12 (purinergic receptor P2Y, G-protein coupled, 12) |
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| Background | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of P2Y12 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
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| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
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| Positive Controls | HepG2 |
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| Target | P2Y12 |
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| Predicted Target Size(KDa) | 39 |
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| Post-translation modification | Disulfide bond | Glycoprotein |
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| Cellular Localization | Cell membrane; Multi-pass membrane protein |
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| Form Supplied | Liquid |
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| Concentration | 1 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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