| Catalog Number | GTX108248 |
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| Product Name | ROCK2-phospho-Y722 antibody |
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| Full Name | Rho-associated, coiled-coil containing protein kinase 2 |
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| Synonyms | ROCK2|KIAA0619|Rho-associated, coiled-coil containing protein kinase 2 |
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| Product Description | Rabbit polyclonal antibody to ROCK2-phospho-Y722 (Rho-associated, coiled-coil containing protein kinase 2) |
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| Background | The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 667 and 727 of Human ROCK2-phospho-Y722 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Application Note | Antibody reactive against peptide, detects immunogen. Further validation in progress. |
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| Positive Controls | Synthetic peptide: 1:8,000 |
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| Target | ROCK2-phospho-Y722 |
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| Predicted Target Size(KDa) | 161 |
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| Cellular Localization | Cytoplasm (By similarity) | Cell membrane; Peripheral membrane protein (By similarity) |
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| Form Supplied | Liquid |
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| Concentration | 0.24 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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