| Catalog Number | GTX108503 |
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| Product Name | LOX 1 antibody |
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| Full Name | oxidized low density lipoprotein (lectin-like) receptor 1 |
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| Synonyms | OLR1|CLEC8A|LOX1|LOXIN|SCARE1|SLOX1|oxidized low density lipoprotein (lectin-like) receptor 1 |
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| Product Description | Rabbit polyclonal antibody to LOX 1 (oxidized low density lipoprotein (lectin-like) receptor 1) |
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| Background | This gene encodes a receptor protein which belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternative transcript variants have been described but their full-length sequence has not been determined. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of Human LOX 1 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Application Note | Antibody reactive against peptide, detects immunogen. Further validation in progress. |
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| Positive Controls | Synthetic peptide: 1:8,000 |
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| Target | LOX 1 |
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| Predicted Target Size(KDa) | 31 |
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| Cellular Localization | Cell membrane; Single-pass type II membrane protein | Secreted |
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| Form Supplied | Liquid |
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| Concentration | 0.99 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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