| Catalog Number | GTX108594 |
|---|
| Product Name | SMAD6 antibody |
|---|
| Full Name | SMAD family member 6 |
|---|
| Synonyms | SMAD6|HsT17432|MADH6|MADH7|SMAD family member 6 |
|---|
| Product Description | Rabbit polyclonal antibody to SMAD6 (SMAD family member 6) |
|---|
| Background | The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene. |
|---|
| Host | Rabbit |
|---|
| Clonality | Polyclonal |
|---|
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 272 and 496 of Human SMAD6 |
|---|
| Antigen Species | Human |
|---|
| Species Cross Reactivity | Human - Not yet tested in other species |
|---|
| Predicted Cross Reactivity Species | mouse(96%), rat(96%), zebra fish(81%) |
|---|
| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
|---|
| Positive Controls | Target recombinant protein |
|---|
| Target | SMAD6 |
|---|
| Predicted Target Size(KDa) | 54 |
|---|
| Cellular Localization | Nucleus |
|---|
| Form Supplied | Liquid |
|---|
| Concentration | 1 mg/ml |
|---|
| Purification | Purified by antigen-affinity chromatography. |
|---|
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
|---|
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
|---|
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
|---|