| Catalog Number | GTX109262 |
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| Product Name | S100A1 antibody |
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| Full Name | S100 calcium binding protein A1 |
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| Synonyms | S100A1|S100|S100-alpha|S100A|S100 calcium binding protein A1 |
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| Product Description | Rabbit polyclonal antibody to S100A1 (S100 calcium binding protein A1) |
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| Background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 64 of Human S100A1 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(93%), rat(93%), cow(98%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | S100A1 |
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| Predicted Target Size(KDa) | 11 |
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| Cellular Localization | Cytoplasm |
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| Form Supplied | Liquid |
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| Concentration | 0.58 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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