| Catalog Number | GTX109578 |
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| Product Name | Hemoglobin gamma A antibody |
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| Full Name | hemoglobin, gamma A |
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| Synonyms | HBG1|HBGA|HBGR|HSGGL1|PRO2979|hemoglobin, gamma A |
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| Product Description | Rabbit polyclonal antibody to Hemoglobin gamma A (hemoglobin, gamma A) |
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| Background | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Protein antigen contains a sequence within a region between amino acids 1 and 130 of human Hemoglobin gamma A |
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| Antigen Species | Human |
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| Predicted Cross Reactivity Species | monkey(96%) |
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| Application Note | Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | Hemoglobin gamma A |
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| Predicted Target Size(KDa) | 16 |
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| Form Supplied | Liquid |
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| Concentration | 1 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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