| Catalog Number | GTX109634 |
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| Product Name | eHAND antibody |
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| Full Name | heart and neural crest derivatives expressed 1 |
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| Synonyms | HAND1|Hxt|Thing1|bHLHa27|eHand|heart and neural crest derivatives expressed 1 |
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| Product Description | Rabbit polyclonal antibody to eHAND (heart and neural crest derivatives expressed 1) |
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| Background | The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 118 and 181 of Human eHAND |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Application Note | Antibody reactive against peptide, detects immunogen. Further validation in progress. |
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| Positive Controls | Synthetic peptide: 1:8,000 |
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| Target | eHAND |
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| Predicted Target Size(KDa) | 24 |
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| Cellular Localization | Nucleus |
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| Form Supplied | Liquid |
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| Concentration | 0.89 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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