| Catalog Number | GTX109658 |
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| Product Name | CPEB antibody |
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| Full Name | cytoplasmic polyadenylation element binding protein 1 |
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| Synonyms | CPEB1|CEBP|CPE-BP1|CPEB|FLJ13203|MGC34136|MGC60106|cytoplasmic polyadenylation element binding protein 1 |
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| Product Description | Rabbit polyclonal antibody to CPEB (cytoplasmic polyadenylation element binding protein 1) |
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| Background | This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 491 and 557 of Human CPEB |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(100%), rat(100%) |
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| Application Note | Antibody reactive against peptide, detects immunogen. Further validation in progress. |
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| Positive Controls | Synthetic peptide: 1:8,000 |
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| Target | CPEB |
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| Predicted Target Size(KDa) | 62 |
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| Cellular Localization | Cytoplasm | P-body | Cytoplasmic granule | Cell junction | synapse | Membrane | postsynaptic cell membrane | postsynaptic density | Cell projection | dendrite |
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| Form Supplied | Liquid |
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| Concentration | 1 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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