| Catalog Number | GTX110101 |
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| Product Name | NRAGE antibody |
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| Full Name | melanoma antigen family D, 1 |
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| Synonyms | MAGED1|DLXIN-1|NRAGE|melanoma antigen family D, 1 |
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| Product Description | Rabbit polyclonal antibody to NRAGE (melanoma antigen family D, 1) |
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| Background | This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 465 and 661 of Human NRAGE |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(98%), rat(98%), cow(100%), pig(100%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | NRAGE |
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| Predicted Target Size(KDa) | 86 |
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| Cellular Localization | Cytoplasm (By similarity) | Cell membrane; Peripheral membrane protein (By similarity) |
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| Form Supplied | Liquid |
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| Concentration | 0.76 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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