| Catalog Number | GTX110705 |
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| Product Name | GADD 45 alpha antibody |
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| Full Name | growth arrest and DNA-damage-inducible, alpha |
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| Synonyms | GADD45A|DDIT1|GADD45|growth arrest and DNA-damage-inducible, alpha |
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| Product Description | Rabbit polyclonal antibody to GADD 45 alpha (growth arrest and DNA-damage-inducible, alpha) |
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| Background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 135 of Human GADD 45 alpha |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(94%), rat(92%), cow(99%), pig(97%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | GADD 45 alpha |
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| Predicted Target Size(KDa) | 18 |
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| Form Supplied | Liquid |
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| Concentration | 0.33 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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