| Catalog Number | GTX110061 |
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| Product Name | 3-oxoacid CoA transferase 1 antibody |
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| Full Name | 3-oxoacid CoA transferase 1 |
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| Synonyms | OXCT1|OXCT|SCOT|3-oxoacid CoA transferase 1 |
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| Product Description | Rabbit polyclonal antibody to 3-oxoacid CoA transferase 1 (3-oxoacid CoA transferase 1) |
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| Background | This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 172 and 421 of 3-oxoacid CoA transferase 1 |
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| Antigen Species | Human |
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| Species Cross Reactivity | Human - Not yet tested in other species |
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| Predicted Cross Reactivity Species | mouse(93%), rat(93%), cow(90%), pig(89%) |
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| Application Note | Antibody reactive against recombinant protein, detects immunogen. Further validation in progress. |
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| Positive Controls | Target recombinant protein |
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| Target | 3-oxoacid CoA transferase 1 |
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| Predicted Target Size(KDa) | 56 |
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| Cellular Localization | Mitochondrion matrix |
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| Form Supplied | Liquid |
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| Concentration | 1 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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