| Catalog Number | GTX101404 |
| Product Name | alpha-2M antibody |
| Full Name | alpha-2-macroglobulin |
| Product Description | Rabbit polyclonal antibody to A2M (alpha-2-macroglobulin) |
| Synonyms | CPAMD5 | DKFZp779B086 | FWP007 | S863-7 | alpha 2M |
| Background | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1158 and 1319 of Human A2M |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human A2M protein. |
| Species Cross Reactivity | Tested with Human antigen. Other species have not been tested. |
| Positive Controls | 293T |
| Target | A2M |
| Predicted Target Size(KDa) | 163.32 |
| Cellular Localization | Secreted |
| Form Supplied | Liquid |
| Concentration | 8.74 mg/ml |
| Purification | Affinity purified by Protein A. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |