click picture to see original size GTX103219 WB Image
Sample(30 ug whole cell lysate)
A:A431(GTX27909)
B:H1299
C:HeLa S3(GTX14654)
D:Hep G2 (GTX27900)
7.5% SDS PAGE
GTX103219 diluted at 1:1000

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Product Information

Product NameCat NoPackagePriceSpecial Price
actinin, alpha 2 antibodyGTX103219100 μlUSD $289.00 -
Qty   Add to CartWish List
Catalog NumberGTX103219
Product Nameactinin, alpha 2 antibody
Full Nameactinin, alpha 2
Product DescriptionRabbit polyclonal antibody to ACTN2 (actinin, alpha 2)
SynonymsCMD1AA
BackgroundAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq]
ClonalityPolyclonal
HostRabbit
ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 347 of Human ACTN2
Antigen SpeciesHuman
Tested ApplicationsWB. The usefulness of this product in other applications has not been determined.
Application NoteSuggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
SpecificityThis antibody is specific to the Human ACTN2 protein.
Species Cross ReactivityHuman - Not yet tested in other species
Positive Controls293T | A431 | H1299 | HeLaS3 | HepG2 | Raji
TargetACTN2
Predicted Target Size(KDa)103.87
Cellular LocalizationCytoplasm | myofibril | sarcomere | Z-disk
Form SuppliedLiquid
Concentration0.98 mg/ml
PurificationPurified by antigen-affinity chromatography.
Storage Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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