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Mouse Human All
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alpha Actinin 2 antibody
- DataSheet
- Bio-information
- Related Products
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| Catalog Number | GTX103219 |
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| Product Name | alpha Actinin 2 antibody |
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| Full Name | actinin, alpha 2 |
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| Synonyms | ACTN2|CMD1AA|actinin, alpha 2 |
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| Product Description | Rabbit Polyclonal alpha Actinin 2 antibody ( actinin, alpha 2) |
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| Background | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq] |
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| Host | Rabbit |
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| Clonality | Polyclonal |
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| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 11 and 347 of alpha Actinin 2 |
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| Antigen Species | Human |
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| Species Cross Reactivity | human, mouse - Not yet tested in other species |
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| Predicted Cross Reactivity Species | rat(91%), cow(99%), zebra fish(92%) |
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| Tested Applications | ICC/IF, Western blot. The usefulness of this product in other applications has not been determined. |
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| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000,IF:1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
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| Positive Controls | 293T | A431 | H1299 | HeLaS3 | HepG2 | Raji | NIH-3T3 |
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| Predicted Target Size(KDa) | 104 |
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| Cellular Localization | 0 |
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| Form Supplied | Liquid |
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| Concentration | 0.98 mg/ml |
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| Purification | Purified by antigen-affinity chromatography. |
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| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
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| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
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| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
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