|Full Name||X-ray repair complementing defective repair in Chinese hamster cells 1|
|Product Description||Rabbit polyclonal antibody to XRCC1 (X-ray repair complementing defective repair in Chinese hamster cells 1)|
|Background||The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]|
|Synonyms||RCC antibody, XRCC1 antibody, "X-ray-repair, complementing defective, repair in Chinese hamster antibody", DNA repair protein XRCC1 antibody, X-ray repair cross-complementing protein 1 antibody, X-ray repair complementing defective repair in Chinese hamster cells 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human XRCC1. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (91%), Dog (90%)|