|Full Name||xylosyltransferase II|
|Product Description||Rabbit Polyclonal antibody to Xylosyltransferase II (xylosyltransferase II)|
|Background||The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. [provided by RefSeq]|
|Synonyms||PXYLT2 antibody, XT-II antibody, XT2 antibody, xylT-II antibody, XYLT2 antibody, xylosyltransferase 2 antibody, peptide O-xylosyltransferase 1 antibody, protein xylosyltransferase 2 antibody, UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase antibody, xylosyltransferase II antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity) , Golgi apparatus membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Xylosyltransferase II. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Japanese medaka, Dog, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Zebrafish (84%), Japanese medaka (82%), Dog (98%), Chicken (93%), Chimpanzee (100%), Bovine (95%)|