|Full Name||Y box binding protein 1|
|Product Description||Rabbit Polyclonal antibody to YB1 (Y box binding protein 1)|
|Background||Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.|
|Synonyms||BP8 antibody , CSDA2 antibody , CSDB antibody , DBPB antibody , MDR NF1 antibody , NSEP1 antibody , Y-box binding protein 1 antibody , YB1 antibody , YB1 antibody , YBX1 antibody|
|Cellular Localization||Cytoplasm , Nucleus|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human YB1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rabbit, Chicken, Sheep, Bovine, Guinea pig|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Xenopus laevis (81%), Rabbit (100%), Chicken (93%), Sheep (98%), Bovine (100%), Guinea pig (98%)|