| Full Name | zinc finger, BED-type containing 3 |
| Product Description | Rabbit polyclonal antibody to ZBED3 |
| Background | Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2. |
| Synonyms | ZBED3, Zinc finger BEDtype domain containing3, Zinc finger BEDtype domain containing 3, Zinc finger BED-type domain containing 3 |
| Specificity | This antibody is specific for ZBED3 C-Terminus |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | ZBED3 |
| Species Reactivity | Human |