| Full Name | zinc finger, BED-type containing 3 |
| Background | Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2. |
| Synonyms | ZBED3, Zinc finger BEDtype domain containing3, Zinc finger BEDtype domain containing 3, Zinc finger BED-type domain containing 3 |
| Specificity | This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | ZBED3 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human ZBED3.The immunogen is located within the last 50 amino acids of ZBED3. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |