ZC3H8 antibody [N1C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||34 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||zinc finger CCCH-type containing 8|
|Product Description||Rabbit polyclonal antibody to ZC3H8 (zinc finger CCCH-type containing 8)|
|Background||Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.|
|Synonyms||Fliz1 antibody, ZC3HDC8 antibody, ZC3H8 antibody, zinc finger CCCH domain-containing protein 8 antibody, zinc finger CCCH type domain containing 8 antibody, zinc finger CCCH-type domain containing 8 antibody, zinc finger CCCH-type containing 8 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human ZC3H8. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (80%), Bovine (82%)|