|Full Name||zinc finger protein of the cerebellum 2|
|Product Description||Rabbit Polyclonal antibody to ZIC2|
|Background||ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.|
|Immunogen||Synthetic peptide: FGRSEQYRQVASPRTDPYS conjugated to KLH, corresponding to amino acids 189-206 of Mouse Zic2.|
|Species Reactivity||Human, Mouse, Dog, Rat, Chimpanzee|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Expected to cross-react with Human, Bovine, Zebrafish|
|Predict Reactivity Note||Expected to cross-react with Human (100% identity with immunogen), Bovine and Zebrafish (83% identity with immunogen) due to sequence homology.|