|Full Name||teashirt zinc finger homeobox 3|
|Product Description||Rabbit polyclonal antibody to ZNF537 (teashirt zinc finger homeobox 3)|
|Background||Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.|
|Synonyms||FLJ54422 antibody, KIAA1474 antibody, TSH3 antibody, ZNF537 antibody, TSHZ3 antibody, zinc finger protein 537 antibody, teashirt homolog 3 antibody, teashirt 3 antibody, teashirt family zinc finger 3 antibody, teashirt zinc finger homeobox 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human ZNF537. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Xenopus laevis|
|Predict Reactivity Note||Human (100%), Mouse (97%), Rat (98%), Xenopus laevis (94%)|