|Full Name||aldehyde dehydrogenase 3 family, member A1|
|Product Description||Rabbit polyclonal antibody to aldehyde dehydrogenase 3A1 (aldehyde dehydrogenase 3 family, memberA1)|
|Background||Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]|
|Synonyms||ALDH3 antibody, ALDHIII antibody, MGC10406 antibody, ALDH3A1 antibody, "aldehyde dehydrogenase, dimeric NADP-preferring antibody", stomach aldehyde dehydrogenase antibody, aldehyde dehydrogenase type III antibody, aldehyde dehydrogenase isozyme 3 antibody, "aldehyde dehydrogenase 3 family, member A1 antibody"|
|Cellular Localization||Cytoplasm |
|Target||aldehyde dehydrogenase 3A1|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human aldehyde dehydrogenase 3A1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Dog|
|Predict Reactivity Note||Human (100%), Mouse (82%), Rat (83%), Dog (91%)|