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1 .GTX106014 alpha 1 Catenin antibody

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alpha 1 Catenin antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsIHC-P, IP, WB
  • Species reactivityHuman, Mouse, Rat
  • Publication  ( 1 )
Cat No: GTX106014
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
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  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
  • Anti-alpha 1 Catenin antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX106014
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
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  • Bio-info
  • Protocol & MSDS
  • Application Information: alpha 1 Catenin antibody

Catalog Number GTX106014
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( 0 )
Publication ( 1 )
Product Name alpha 1 Catenin antibody
See all alpha 1 Catenin products
ApplicationsIHC-P, IP, WB
Application Note
Suggested dilutionReference
IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*  
ImmunoprecipitationAssay-dependent dilution Y
Western Blot (WB)1:500-1:10000*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size100 kDa (note) IsoForm (32)
Positive Controls293T , A431 , mouse brain , rat brain
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography.

  • Specifications: alpha 1 Catenin antibody

Full Namecatenin (cadherin-associated protein), alpha 1, 102kDa
BackgroundAssociates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
SynonymsCAP102 antibody, FLJ36832 antibody, FLJ52416 antibody, CTNNA1 antibody, "cadherin-associated protein,102kDa antibody", alpha-catenin antibody, alphaE-catenin antibody, catenin alpha-1 antibody, renal carcinoma antigen NY-REN-13 antibody, alpha-E-catenin antibody, alpha E-catenin antibody, "catenin (cadherin-associated protein), alpha 1, 102kDa antibody", alpha catenin antibody, alpha catenin
Cellular LocalizationCytoplasm , cytoskeleton , Cell junction , adherens junction , Cell membrane
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant protein encompassing a sequence within the center region of human alpha 1 Catenin. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
Zebrafish, Xenopus laevis, Rabbit, Rhesus Monkey, Bovine
Predict Reactivity NoteZebrafish (93%), Xenopus laevis (96%), Rabbit (100%), Rhesus Monkey (99%), Bovine (100%)
ConjugationUnconjugated

  • Storage Conditions: alpha 1 Catenin antibody

Storage Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Signal Transduction > ECM/Cytoskeleton > Cell Adhesion
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alpha 1 Catenin antibody validated data
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
    • GTX106014 WB Image
      Sample (30 ug of whole cell lysate)
      A: 293T
      7.5% SDS PAGE
      GTX106014 diluted at 1:5000
      Top
  • Anti-alpha 1 Catenin antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX106014
    • GTX106014 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using alpha Catenin(GTX106014) antibody at 1:250 dilution.
      Top
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
    • GTX106014 WB Image
      Sample (50 ug of whole cell lysate)
      A: Mouse brain
      7.5% SDS PAGE
      GTX106014 diluted at 1:1000
      Top
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
    • GTX106014 WB Image
      Rat tissue extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with alpha Catenin antibody (GTX106014) diluted at 1:500.
      Top
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
    • GTX106014 WB Image
      Sample (30 ug of whole cell lysate)
      A: 293T
      7.5% SDS PAGE
      GTX106014 diluted at 1:5000
      Top
  • Anti-alpha 1 Catenin antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX106014
    • GTX106014 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using alpha Catenin(GTX106014) antibody at 1:250 dilution.
      Top
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
    • GTX106014 WB Image
      Sample (50 ug of whole cell lysate)
      A: Mouse brain
      7.5% SDS PAGE
      GTX106014 diluted at 1:1000
      Top
  • Anti-alpha 1 Catenin antibody used in Western Blot (WB). GTX106014
    • GTX106014 WB Image
      Rat tissue extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with alpha Catenin antibody (GTX106014) diluted at 1:500.
      Top
Back to Top
  • Reference for alpha 1 Catenin antibody
Application References Application Reactivity
Sundararaman B et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell 61 (6):903-13 (2016). IP Human
Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensCTNNA11495P35221116805NP_00127723888.7
Homo sapiensCTNNA11495P35221116805NP_00127723986.66
Homo sapiensCTNNA11495P35221116805NP_00127724159.56
Homo sapiensCTNNA11495P35221116805NP_001310911100.09
Homo sapiensCTNNA11495P35221116805NP_001310912100.09
Homo sapiensCTNNA11495P35221116805NP_001310913100.09
Homo sapiensCTNNA11495P35221116805NP_00131091499.15
Homo sapiensCTNNA11495P35221116805NP_00131091596.83
Homo sapiensCTNNA11495P35221116805NP_00131091659.56
Homo sapiensCTNNA11495P35221116805NP_00131091759.56
Homo sapiensCTNNA11495P35221116805NP_00131091859.56
Homo sapiensCTNNA11495P35221116805NP_00131091959.56
Homo sapiensCTNNA11495P35221116805NP_00131092059.56
Homo sapiensCTNNA11495P35221116805NP_00131092159.56
Homo sapiensCTNNA11495P35221116805NP_00131092259.56
Homo sapiensCTNNA11495P35221116805NP_00131092359.56
Homo sapiensCTNNA11495P35221116805NP_00131092459.56
Homo sapiensCTNNA11495P35221116805NP_00131092559.56
Homo sapiensCTNNA11495P35221116805NP_00131092659.56
Homo sapiensCTNNA11495P35221116805NP_00131092759.56
Homo sapiensCTNNA11495P35221116805NP_00131092859.56
Homo sapiensCTNNA11495P35221116805NP_00131092959.56
Homo sapiensCTNNA11495P35221116805NP_00131093054.69
Homo sapiensCTNNA11495P35221116805NP_00131093547.04
Homo sapiensCTNNA11495P35221116805NP_00131093647.04
Homo sapiensCTNNA11495P35221116805NP_00131093747.04
Homo sapiensCTNNA11495P35221116805NP_00131093847.04
Homo sapiensCTNNA11495P35221116805NP_00131093947.04
Homo sapiensCTNNA11495P35221116805NP_00131094056.3
Homo sapiensCTNNA11495P35221116805NP_00131094150.33
Homo sapiensCTNNA11495P35221116805NP_00131094250.33
Homo sapiensCTNNA11495P35221116805NM_001903NP_001894100.09

Cross-react Bioinfo
SpeciesGene nameGene IDSwissProtIsoform (mRNA)Protein Accession#MW
Mus musculusCtnna112385P26231, Q545R0NM_009818NP_033948100.13
Rattus norvegicusCtnna1307505Q5U302NM_001007145NP_001007146100.26
    *MSDS
    MSDS-Glycerol.pdf
    MSDS-Thimerosal.pdf
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