|Full Name||adrenergic, alpha-1A-, receptor|
|Product Description||Rabbit Polyclonal antibody to alpha 1a Adrenergic Receptor (adrenergic, alpha-1A-, receptor)|
|Background||Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq]|
|Synonyms||ADRA1C antibody, ADRA1L1 antibody, ALPHA1AAR antibody, ADRA1A antibody, "adrenergic, alpha-1A-, receptor variant 3 antibody", G protein coupled receptor antibody, "adrenergic, alpha-1A-, receptor variant 8 antibody", alpha-1A adrenoreceptor antibody, alpha-1C adrenergic receptor antibody, "adrenergic, alpha-1A-, receptor variant 5 antibody", alpha-1A adrenoceptor antibody, "adrenergic, alpha-1A-, receptor variant 1 antibody", alpha-1A adrenergic receptor antibody, "adrenergic, alpha-1A-, receptor antibody"|
|Cellular Localization||Cell membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human alpha 1a Adrenergic Receptor. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rabbit, Rhesus Monkey, Bovine, Guinea pig|
|Predict Reactivity Note||Dog (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%), Guinea pig (100%)|