|Full Name||adrenergic, alpha-1B-, receptor|
|Product Description||Rabbit polyclonal antibody to alpha 1b Adrenergic Receptor (adrenergic, alpha-1B-, receptor)|
|Background||Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq]|
|Synonyms||ADRA1 antibody, ALPHA1BAR antibody, ADRA1B antibody, alpha-1B-adrenergic receptor antibody, alpha-1B adrenoreceptor antibody, alpha-1B adrenergic receptor antibody, alpha-1B adrenoceptor antibody, "adrenergic, alpha-1B-, receptor antibody"|
|Cellular Localization||Cell membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 1b Adrenergic Receptor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Dog, Rabbit, Bovine|
|Predict Reactivity Note||Human (100%), Rat (100%), Dog (100%), Rabbit (100%), Bovine (100%)|