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  • alpha 2a Adrenergic Receptor antibody

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1 .GTX80800 alpha 2a Adrenergic Receptor antibody

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alpha 2a Adrenergic Receptor antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsICC/IF, IHC-Fr
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX80800
Package Price Qty
150 μlUSD 459.00
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  • Anti-alpha 2a Adrenergic Receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80800
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  • Datasheet
  • Application Information: alpha 2a Adrenergic Receptor antibody

Catalog Number GTX80800
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Product Name alpha 2a Adrenergic Receptor antibody
See all alpha 2a Adrenergic Receptor products
ApplicationsICC/IF, IHC-Fr
Application NoteFor IHC-Fr: Use at a dilution of 1:100-1:500. Antiserum was used on perfusion fixed tissue. Perfusion: 1) calcium-free Tyrode’s solution, 2) paraformaldehyde-picric acid fixative, and 3) 10% sucrose in PBS as a cryo-protectant. Desired tissues were dissected and stored overnight in 10% sucrose in PBS. Optimal dilutions/concentrations should be determined by the researcher.
Form SuppliedLiquid
Concentration0.47 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified IgG

  • Specifications: alpha 2a Adrenergic Receptor antibody

Full Nameadrenergic, alpha-2A-, receptor
BackgroundAlpha 2A, 2B, and 2C adrenergic receptors are seven transmembrane receptors that couple to inhibitory G-proteins. Alpha 2C has a wide distribution pattern in the CNS. On neurons Alpha 2 adrenergic receptors are located on both pre- and postsynaptic domains where they mediate an inhibitory role in the central and peripheral nervous system. Alpha 2C has a wide distribution pattern in the CNS. At the spinal cord level the vast majority of alpha 2C is not of primary afferent origin; however, a small fraction of neurons in DRG do express mRNA for alpha 2C and harbor the protein. Colocalization has been observed between alpha 2C and enkephalin in the spinal cord dorsal horn, suggesting that alpha 2C may be expressed by a subset of spinal interneurons. The distribution pattern of alpha 2C suggests functions at several levels in the brain. Antibody showed positive staining in rat spinal cord dorsal horn, ventral horn motor neurons and retina. When examined in other brain regions known to express ?2A staining was not observed.
SynonymsADRA2A, P08913, ADRA2, ADRAR, 150, alpha2a Adrenergic receptor, ZNF32, ALPHA2AAR, ADRA2R, alpha 2a Adrenergic receptor, 104210
HostRabbit
ClonalityPolyclonal
ImmunogenPeptide - (C)KASRWRGRGNREKR (Cysteine added for conjugation)
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: alpha 2a Adrenergic Receptor antibody

Storage InstructionUpon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Disease Related > Alzheimer's disease
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  • Neuroscience > Disorder > Alzheimer's disease
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alpha 2a Adrenergic Receptor antibody validated data
  • Anti-alpha 2a Adrenergic Receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80800
    • GTX80800 ICC/IF Image
      Alpha 2 adrenergic receptor labeling in rat cryostat section of rat brain. Labeling is confined to synaptic boutons (red). Tissue nuclei were counterstasined with DAPI (blue).
      Top
  • Anti-alpha 2a Adrenergic Receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX80800
    • GTX80800 ICC/IF Image
      Alpha 2 adrenergic receptor labeling in rat cryostat section of rat brain. Labeling is confined to synaptic boutons (red). Tissue nuclei were counterstasined with DAPI (blue).
      Top
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