|Full Name||adducin 1 (alpha)|
|Product Description||Rabbit Polyclonal antibody to alpha Adducin (adducin 1 (alpha))|
|Background||Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq]|
|Synonyms||ADD1 Antibody, ADDA Antibody, adducin 1 (alpha) Antibody|
|Cellular Localization||Cytoplasm , cytoskeleton , Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human alpha Adducin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (81%), Rhesus Monkey (97%), Bovine (90%)|