|Full Name||actin, alpha 1, skeletal muscle|
|Product Description||Rabbit Polyclonal antibody to alpha Skeletal Muscle Actin (actin, alpha skeletal muscle)|
|Background||The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq]|
|Synonyms||ACTA antibody, ASMA antibody, CFTD antibody, CFTD1 antibody, CFTDM antibody, MPFD antibody, NEM1 antibody, NEM2 antibody, NEM3 antibody, ACTA1 antibody, alpha-actin-1 antibody, alpha skeletal muscle actin antibody, "actin, alpha skeletal muscle antibody", "actin, alpha 1, skeletal muscle antibody"|
|Cellular Localization||Cytoplasm , cytoskeleton |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human alpha Skeletal Muscle Actin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Japanese medaka, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Rat (100%), Japanese medaka (98%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Bovine (100%)|