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alpha Smooth Muscle Actin antibody [1A4] (ready-to-use)

Anti-alpha Smooth Muscle Actin antibody [1A4] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73419

Cat. No. GTX73419

Host

Mouse

Clonality

Monoclonal

Clone Name

1A4

Isotype

IgG2a

Application

IHC-P, IHC-Fr, FACS

Reactivity

Human, Mouse, Rat
Package
6 ml ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.

Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Product Note

This antibody is specific to α-smooth muscle isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. This antibody does not cross-react with β and γ-cytoplasmic, α-sarcomeric and α-myocardial actin isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

BALB/C mice were injected with N-terminal decapeptide of α-smooth muscle actin.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_374897

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

actin alpha 2, smooth muscle , ACTSA

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]

Database

  • Gene ID: 59 ACTA2
  • UniProt: P62736 ACTA2

Research Area

DATA IMAGES

Anti-alpha Smooth Muscle Actin antibody [1A4] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX73419

GTX73419 IHC-P Image

IHC-P analysis of human colon tissue using GTX73419 alpha Smooth Muscle Actin antibody [1A4] (ready-to-use).

REFERENCE

REVIEW

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Application Reference
Clone Reference
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399