alpha Tubulin 1A antibody
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||50 kDa (note)
|Positive Controls||Jurkat , Raji , 293T , A431 , HeLa , HepG2 , H1299 , HCT116 , MCF-7 , NT2D1 , PC-3 , U87-MG , NIH-3T3 , mouse brain , rat brain , Drosophila|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tubulin, alpha 1a|
|Product Description||Rabbit Polyclonal antibody to alpha Tubulin 1A (tubulin, alpha 1a)|
|Background||Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. [provided by RefSeq]|
|Synonyms||B-ALPHA-1 antibody, FLJ25113 antibody, LIS3 antibody, TUBA3 antibody, TUBA1A antibody, tubulin B-alpha-1 antibody, hum-a-tub1 antibody, "tubulin, alpha, brain-specific antibody", hum-a-tub2 antibody, tubulin alpha-1A chain antibody, "tubulin, alpha 3 antibody", alpha-tubulin 3 antibody, tubulin alpha-3 chain antibody, "tubulin, alpha 1a antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human alpha Tubulin 1A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Drosophila, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Pig, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (100%), Xenopus laevis (98%), Pig (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|