beta-Adaptin antibody [N3C1], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||105 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||adaptor-related protein complex 1, beta 1 subunit|
|Product Description||Rabbit polyclonal antibody to beta-Adaptin (adaptor-related protein complex 1, beta 1 subunit)|
|Background||Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist. [provided by RefSeq]|
|Synonyms||ADTB1 antibody, AP105A antibody, BAM22 antibody, CLAPB2 antibody, AP1B1 antibody, adapter-related protein complex 1 subunit beta-1 antibody, Golgi adaptor HA1/AP1 adaptin beta subunit antibody, AP-1 complex subunit beta-1 antibody, adaptor protein complex AP-1 subunit beta-1 antibody, plasma membrane adaptor HA2/AP2 adaptor beta subunit antibody, beta-1-adaptin antibody, beta-adaptin 1 antibody, beta-prime-adaptin antibody, clathrin assembly protein complex 1 beta large chain antibody, beta1-adaptin antibody, "adaptor-related protein complex 1, beta 1 subunit antibody"|
|Cellular Localization||Golgi apparatus , Cytoplasmic vesicle , clathrin-coated vesicle membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human beta-Adaptin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Bovine|
|Predict Reactivity Note||Rat (98%), Zebrafish (99%), Bovine (100%)|