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  • beta Amyloid (1-40/42) antibody [BDI910], C-term

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1 .GTX44422 beta Amyloid (1-40/42) antibody [BDI910], C-term

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beta Amyloid (1-40/42) antibody [BDI910], C-term


  • Host / ClonalityMouse Monoclonal
  • Clone NameBDI910
  • ApplicationsELISA, ICC/IF, WB
  • Species reactivityHuman
Cat No: GTX44422
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50 μgUSD 319.00
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  • Application Information: beta Amyloid (1-40/42) antibody [BDI910], C-term

Catalog Number GTX44422
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Product Name beta Amyloid (1-40/42) antibody [BDI910], C-term
See all beta Amyloid products
ApplicationsELISA, ICC/IF, WB
Application Note
Suggested dilutionReference
ELISA0.05 µg/ml *  
Immunocytochemistry/ Immunofluorescence (ICC/IF)0.1-1 µg/ml *  
Western Blot (WB)0.1-1 µg/ml *  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Form SuppliedLiquid
Concentration0.10 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by thiophilic adsorption and size exclusion chromatography
Purification NoteFrom tissue culture supernatant

  • Specifications: beta Amyloid (1-40/42) antibody [BDI910], C-term

Full Nameamyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
BackgroundThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
SynonymsAPPI Antibody , APP Antibody , ABETA Antibody , AD1 Antibody , CVAP Antibody , CTFGAMMA Antibody , PN II Antibody , PN2 Antibody , ABPP Antibody , AAA Antibody
Cellular LocalizationCell surface protein that rapidly becomes internalized via clathrin-coated pits. During maturation, the immature APP (N-glycosylated in the endoplasmic reticulum) moves to the Golgi complex where complete maturation occurs (O-glycosylated and sulfated). A
SpecificityInteracts with the C-termini of both beta Amyloid 1-40 and 1-42.
HostMouse
ClonalityMonoclonal
Clone NameBDI910
IsotypeIgG1
ImmunogenC-terminal peptide conjugated to KLH.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: beta Amyloid (1-40/42) antibody [BDI910], C-term

Storage Buffer2X PBS, PEG, Sucrose, 0.09% sodium azide
Storage InstructionKeep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Apoptosis > Nervous system > Neuron
  • Cell Biology > Apoptosis > Nervous system > Neuron
  • Cell Biology > Endocytosis
  • Disease Related > Alzheimer's disease
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beta Amyloid (1-40/42) antibody [BDI910], C-term validated data
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