beta Tubulin 3/ Tuj1 antibody [GT886]
|Applications||ICC/IF, IHC-Fr, IP, WB|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||50 kDa (note)
|Positive Controls||HeLa , SK-N-SH , IMR32 , SK-N-AS , Neuro2A , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||tubulin, beta 3 class III|
|Product Description||Mouse Monoclonal antibody [GT886] to beta Tubulin 3/ TUJ1 (tubulin, beta 3 class III)|
|Background||This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq]|
|Synonyms||CDCBM Antibody , CFEOM3A Antibody , TUBB4 Antibody , tubulin, beta 3 class III Antibody , beta-4 Antibody , TUBB3 Antibody, TUJ1 Antibody|
|Specificity||beta III Tubulin antibody [GT886] specifically recognizes endogenous levels of beta III Tubulin based on the immunogen sequence.|
|Target||beta Tubulin 3/ TUJ1|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human beta III Tubulin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%), Bovine (100%)|