| Background | The betaIII-tubulin isotype is present dominantly in cells of neuronal origin and it is one of the earliest marker of neuronal differentiation. Class III beta-tubulin, is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The neuron-associated class III beta-tubulin isotype is most abundant in cells of neuronal origin but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues. |
| Specificity | Sequence ESESQGPK (aa 441-448) of human class III beta-tubulin specific for neurones |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | TU-20 |
| Isotype | IgG1 |
| Immunogen | Peptide - (C)441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide. |
| Species Reactivity | Human, Mouse, Pig, Rat, Baboon, Carp, Hamster, Mammal, Bovine |
| Conjugation | FITC |
| Conjugation Note | The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC. |