betaENaC antibody [N2C1], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||73 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||sodium channel, nonvoltage-gated 1, beta|
|Product Description||Rabbit polyclonal antibody to beta ENaC (sodium channel, nonvoltage-gated 1, beta)|
|Background||Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq]|
|Synonyms||BESC1 antibody, ENaCb antibody, ENaCbeta antibody, SCNEB antibody, SCNN1B antibody, amiloride-sensitive sodium channel subunit beta antibody, amiloride-sensitive sodium channel subunit beta 1 antibody, epithelial Na(+) channel subunit beta antibody, epithelial sodium channel beta-2 subunit antibody, epithelial sodium channel beta-3 subunit antibody, nasal epithelial sodium channel beta subunit antibody, nonvoltage-gated sodium channel 1 subunit beta antibody, beta-NaCH antibody, beta-ENaC antibody, "sodium channel, nonvoltage-gated 1, beta antibody"|
|Cellular Localization||Apical cell membrane; Multi-pass membrane protein |
|Target||beta ENaC |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human betaENaC. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Guinea pig|
|Predict Reactivity Note||Dog (82%), Guinea pig (80%)|