| Full Name | FBJ murine osteosarcoma viral oncogene homolog |
| Product Description | Rabbit Polyclonal antibody to C-Fos |
| Background | Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. |
| Synonyms | AP-1, C-FOS, FOS, proto-oncogene c-Fos, FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS), cellular oncogene c-fos, G0/G1 switch regulatory protein 7, activator protein 1, FBJ murine osteosarcoma viral oncogene homolog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | C-Fos |
| Immunogen | Peptide sequence around aa.28~32( S-Y-Y-H-S) derived from Human C-Fos. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Rat |