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  • c-Kit (phospho Tyr568/Tyr570) antibody

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1 .GTX25616 c-Kit (phospho Tyr568/Tyr570) antibody

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c-Kit (phospho Tyr568/Tyr570) antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsWB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX25616
Package Price Qty
50 μlUSD 319.00
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  • Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616
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  • Datasheet
  • Application Information: c-Kit (phospho Tyr568/Tyr570) antibody

Catalog Number GTX25616
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Product Name c-Kit (phospho Tyr568/Tyr570) antibody
See all c-Kit products
ApplicationsWB
Application NoteWB: 1/1000 Detects a band of approximately 145 kDa. Optimal dilutions/concentrations should be determined by the end user.
Positive ControlsM07e cells + or - SCF
Form SuppliedLiquid
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration)
PurificationImmunogen affinity purified
Purification NoteThe antibody has been negatively preadsorbed using a non-phosphopeptide corresponding to the site of phosphorylation to remove antibody that is reactive with non-phosphorylated c Kit protein. The final product is generated by affinity chromatography using

  • Specifications: c-Kit (phospho Tyr568/Tyr570) antibody

Full Namev-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Backgroundc Kit, also known as CD117 and stem cell factor receptor, is a 145 kDa transmembrane tyrosine kinase encoded by the c Kit proto oncogene. c Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosines 568 and 570 of c Kit allows binding and activation of Src family kinases.
SynonymsCKit, KIT, CD117, P10721, SCFR, C-Kit, PBT, 164920, 3815, c Kit, c-Kit (phospho Y568/Y570), c-Kit (phospho Tyr568/Tyr570), c-Kit (pY568/pY570), c-Kit (pTyr568/pTyr570), c-Kit phospho Y568/Y570, c-Kit phospho Tyr568/Tyr570, Phospho c-Kit (Y568/Y570), Phosp
Cellular LocalizationType I membrane protein.
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenSynthetic phosphopeptide derived from the region of human c-Kit that contains tyrosines 568 and 570.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: c-Kit (phospho Tyr568/Tyr570) antibody

Storage BufferPreservative: 0.05% Sodium Azide; Constituents: PBS, 50% glycerol, 1mg/ml BSA (IgG, protease free). pH 7.3
Storage InstructionAliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Leukemia > Myeloid > AML
  • Cancer > Type of cancer > Liver
  • Cancer > Type of cancer > Lung > Other
  • Cancer > Type of cancer > Pancreatic
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c-Kit (phospho Tyr568/Tyr570) antibody validated data
  • Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616
    • GTX25616 WB Image
      Extracts prepared from M07e cells left untreated (1) or treated (2-5) with SCF were resolved by SDS-PAGE on a 10% Tris-glycine gel and transferred to PVDF. Membranes were blocked with a 5% BSA-TBST buffer overnight at 4°C
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  • Anti-c-Kit (phospho Tyr568/Tyr570) antibody used in Western Blot (WB). GTX25616
    • GTX25616 WB Image
      Extracts prepared from M07e cells left untreated (1) or treated (2-5) with SCF were resolved by SDS-PAGE on a 10% Tris-glycine gel and transferred to PVDF. Membranes were blocked with a 5% BSA-TBST buffer overnight at 4°C
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All products are for research use only—Not for use in diagnostic procedures.