|Full Name||carboxypeptidase N, polypeptide 1|
|Product Description||Rabbit Polyclonal antibody to carboxypeptidase N1 (carboxypeptidase N, polypeptide 1)|
|Background||Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq]|
|Synonyms||CPN antibody, FLJ40792 antibody, SCPN antibody, CPN1 antibody, carboxypeptidase N polypeptide 1 50 kD antibody, arginine carboxypeptidase antibody, carboxypeptidase N catalytic chain antibody, serum carboxypeptidase N antibody, carboxypeptidase N catalytic subunit antibody, carboxypeptidase N small subunit antibody, lysine carboxypeptidase antibody, plasma carboxypeptidase B antibody, kininase I antibody, kininase-1 antibody, anaphylatoxin inactivator antibody, "carboxypeptidase N, polypeptide 1 antibody"|
|Cellular Localization||Secreted , extracellular space |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human carboxypeptidase N1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (87%), Rat (86%), Bovine (89%)|