Product Name
Beta Endorphin antibody
Catalog Number
GTX74202
Product Description:
Rabbit polyclonal to Beta Endorphin
Application Note:
For IHC-Fr: Use at a dilution of 1:300 - 1:3,000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Background:
Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. ß-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). ß-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the µ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects.
Cross Reactivity:
Rat and Camel - Not yet tested in other species
Purity:
Unpurified
Storage Instruction:
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Concentration:
whole antiserum
Storage Buffer:
Phosphate buffered saline containing 0.3% Triton, 0.09% sodium azide and 1% BSA
Target Protein:
Beta endorphin 1-27
Purification Note:
From polyclonal serum
Clonality:
Polyclonal
Epitope:
Not yet determined
Tested Applications:
IHC (Frozen sections). The usefulness of this product in other applications has not been determined.
Form:
Liquid
Specificity:
This antibody blocks with beta endorphin 1-27. Cells and fibers are found in the arcuate nucleus in rat brain of 4% FA perfused tissue.
Immunogen:
Beta Endorphin: Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His (camel)
Host:
Rabbit
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