Product Name
Cytochrome P450 1A1 Antibody
Catalog Number
GTX74412
Product Description:
Rabbit Antibody to Human Cytochrome P450 1A1
Application Note:
This antibody is not suitable for Western blot analysis. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Background:
Recognizes human cytochrome p450 1A1 (CYP1A1). P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members:CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1. I a neutralizing antibody which is a potent inhibitor of CYP1A1 and CYP2C8 activity.
Cross Reactivity:
Human - Not yet tested in other species
Purity:
Unpurified
Concentration:
Not determined
Storage Buffer:
Contains no preservatives
Target Protein:
CYP1A1
Clonality:
Polyclonal
Tested Applications:
Functional studies. The usefulness of this product in other applications has not been determined.
Form:
Liquid
Immunogen:
Purified human CYP1A1 expressed in E.Coli
Host:
Rabbit
Storage :
Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
|
| Please tell us about your experience or submit a specific inquiry about this product. |
