Product Name
14-3-3 zeta phospho S58 antibody
Catalog Number
GTX14127
Product Description:
Rabbit polyclonal to 14-3-3 zeta phospho S58
Application Note:
IHC-P: Use at a dilution of 1:50-1:100. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Tested Applications:
IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined.
Background:
This antibody provides a powerful tool for the discovery and characterization of potential 14-3-314-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, theta, epsilon, zeta, sigma, and nu. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzyme activity etc.binding proteins containing this motif and for high throughput drug discovery.
Clonality:
Polyclonal
Host:
Rabbit
Isotype:
IgG
Cross Reactivity:
Human, Mouse and Rat - Not yet tested in other species
Target Protein:
1
Form:
Liquid
Purity:
Affinity purified with antigen
Purification Note:
From polyclonal serum
Storage Buffer:
Phosphate buffered saline, pH 7.3, 50% glycerol and 150mM NaCl containing 0.02% sodium azide
Storage Instruction:
Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
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