Product Name
14-3-3 gamma (clone HS23) Antibody
Catalog Number
GTX30643
Product Description:
Mouse monoclonal to 14-3-3 gamma (clone HS23)
Manufacturer & Mfg Part#:
Novus NB 100-407
Application Note:
This antibody can be used in Western Blot where a distinct band around 33 kDa is detected.
Suggested working dilutions: *
Western Blot - 1:1,000
*The investigator should determine the optimal working dilution for a specific application.
Tested Application:
Western blot. The usefulness of this product in other applications has not been determined.
Background:
14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a proteinís function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints.
Clonality:
monoclonal
Clone Number:
HS23
Specificity:
This antibody is specific for human 14-3-3 gamma.
Immunogen:
This antibody was raised against an N-terminal
fragment of human 14-3-3 gamma.
Host:
Mouse
Isotype:
IgG1
Cross-Reactivity:
GTX30643 reacts with the human form of intact, non-modified N-terminus 14-3-3 gamma. The naturally occurring form of 14-3-3 gamma in which the N-terminus Met is removed and the Val is acetylated is not recognized by this antibody. Other species have not been tested.
Positive Control:
HeLa whole cell lysate
Target Protein:
14-3-3 gamma
Form:
0.1 ml of raw mouse ascites [6.8 mg/ml], containing 0.1% Sodium Azide.
Concentration:
6.8 mg/ml
Storage:
Store at 4 degrees Celcius. Aliquot and store at -20 degrees Celcius for long-term storage. Avoid repeated freeze-thaws.
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