Product Name
TRIM23 antibody
Catalog Number
GTX100057
Product Description:
Rabbit Polyclonal to TRIM23
Manufacturer & Mfg Part#:
GeneTex GTX100057
Application Note:
Suggested starting dilutions are as follows. WB: 1:2,000-1:10,000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Tested Application:
Western blot. The usefulness of this product in other applications has not been determined.
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Clonality:
Polyclonal
Immunogen:
Synthetic peptide - Containing amino acids between 1-100.
Host:
Rabbit
Cross-Reactivity:
Human - Not yet tested in other species
Target:
TRIM23
Target Cal MW:
64.1 kD
Localization:
Cell membrane
Form Supplied:
Liquid
Concentration:
1 mg/ml
Purity:
Affinity purified by antigen
Purification Note:
From polyclonal antiserum
Storage buffer:
Phosphate-buffered saline, pH 7.2, containing 0.01% thimerosal as a preservative.
Storage Conditions:
Store as a concentrated solution. Store at 4ˇăC short term - For long term storage aliquot and store at -20ˇăC or below. Avoid freeze/thaw cycles.
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