Product Name
DNA polymerase delta
Catalog Number
GTX70151
Product Description:
Mouse polyclonal antiserum to human DNA polymerase delta
Manufacturer & Mfg Part#:
GeneTex GTX70151
Application Note:
For WB: Use at a dilution of 1:500. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Background:
DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3' to 5' exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex
Purity:
Unpurified
Expression system:
pQE-30
Storage Buffer:
N/A
Cross-Reactivity:
Human - Not yet tested in other species
Target Protein:
DNA polymerase delta
Purification Note:
From polyclonal serum
Clonality:
Polyclonal
Tested Applications:
Western blot. The usefulness of this product in other applications has not been determined.
Positive Control:
HeLa
Form:
Liquid
Isotype:
IgG
Immunogen:
Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.
Host:
Mouse
Storage:
For long term storage, please keep at -70°C or below. Avoid repeared freeze-thaw cycles.
General References:
1. Liu, L et al. (2000). Identification Of A Fourth Subunit Of Mammalian DNA Polymerase delta. J. Biol. Chem. 275:18739
2000
10751307
2. Jonsson, ZO. (1997). Proliferating Cell Nuclear Antigen: More Than A Clamp For DNA Polymerases. Bioessays. 19:967.
1997
9394619
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