Product Name
NPGPx (GPX7) [2704] antibody
Catalog Number
GTX70267
Product Description:
Mouse monoclonal [2704] to GPX7
Manufacturer & Mfg Part#:
GeneTex GTX70267
Application Note:
For IHC-P: Use at a dilution of 1:200-1:500. For WB: Use at a dilution of 1:500-1:2000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Background:
Human GPX7 (also known as glutathione peroxidase 6) is believed to be a member of the glutathione peroxidase family of proteins. These proteins play important roles in cellular defense mechanisms against oxidative damage. This is a ccomplished by catalyzing the reduction of hydroperoxides and hydrogen peroxide through the reducing substrate, glutathione.
Target Protein MW:
18
Purity:
Protein G Affinity Purified
Expression system:
pQE
Myeloma:
NS1
Concentration:
1 mg/ml
Storage Buffer:
Phosphate-buffered saline, pH 7.4, containing no preservatives
Cross-Reactivity:
Human - Not yet tested in other species
Target Protein:
GPX7
Purification Note:
From ascitic fluid
Clonality:
Monoclonal
Tested Applications:
IHC (Formalin-fixed paraffin-embedded sections), Western blot. The usefulness of this product in other applications has not been determined.
Positive Control:
HeLa
Form:
Liquid
Isotype:
IgG
Immunogen:
Human GPX7
Host:
Mouse
Storage:
Store at -80 °C. Avoid repeat freeze-thaw cycles.
General References:
1. Georgiou, G. 2002. Cell 111:607-610
2002
12464172
Specific References:
1. Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YCJ, Desai KV, Green JE, Chen PL, Lee WH. Identification of a Novel Putative Non-Selenocysteine Containing Phospholipid Hyproperoxide Glutathione Peroxidase (NPGPx) Essential for Alleviating Oxidative Stress Generated from Polyunsaturated Fatty Acids in Breast Cancer Cells. J Biol Chem (2004), 279:43522.
2004
15294905
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