Product Name
XPC (N-terminus) Antibody
Catalog Number
GTX70308
Product Description:
Rabbit polyclonal antibody to human XPC ( amino terminus )
Manufacturer & Mfg Part#:
GeneTex GTX70308
Application Note:
Not tested in other applications. Optimal dilutions/concentratons should be determined by the researcher.
Background:
Human XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair.
Target Protein MW:
Protein migrates at ~120-125 kD
Purity:
Affinity purified with antigen
Concentration:
0.5 mg/ml
Storage Buffer:
Phosphate-buffered saline, pH 7.2, containing no preservatives
Cellular Localization:
Nuclear
Cross-Reactivity:
Human - Not yet tested in other species
Target Protein:
Human XPC
Clonality:
Polyclonal
Epitope:
Amino terminus of human XPC
Target Protein Size:
Protein migrates at ~125 kD
Tested Applications:
Western blot. The usefulness of this product in other applications has not been determined.
Positive Control:
HeLa whole cell lysate
Form:
Liquid
Isotype:
IgG
Specificity:
Human XPC
Immunogen:
Peptide conjugated to a carrier protein
Host:
Rabbit
Storage:
For long term storage, please keep at -70°C or below. Avoid repeared freeze-thaw cycles.
General References:
1. de Laat, WL., et al. (1999). Molecular mechanism of nucleotide excision repair. Genes Dev. 13:768.
1999
10197977
2. Aboussekhra, A., et al. (1995). Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 80:859-68.
1995
7697716
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