Product Name
FANCD2 (Fanconi anemia D2) antibody
Catalog Number
GTX70314
Product Description:
Mouse Monoclonal to human FANCD2 ( Fanconi anemia D2 ) Antibody [Clone 6]
Manufacturer & Mfg Part#:
GeneTex GTX70314
Application Note:
For WB: Use at an assay dependent dilution. Predicted molecular weight: 28 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Background:
Fanconi Anemia Complementation Group D2 (FANCD2) protein is one of at least six factors shown to be involved in the autosomal-recessive cancer-prone disorder, Fanconi Anemia (FA). FA group D has been shown to be comprised of two separate proteins, FANCD1 and FANCD2. Mutations in BRCA2 can cause FANCD1. FANCD2 has been shown to colocalize with BRCA1 in ionizing radiation-induced foci. FANCD2 is involved in genomic resistance to DNA cross-linking reagents, and the arrest of DNA synthesis following exposure to ionizing radiation. FANCD2 has been shown to directly interact with NBS1
Immunogen:
Human FANCD2 fusion protein
Cross Reactivity:
Human - Not yet tested in other species
Tested Applications:
Western blot. The usefulness of this product in other applications has not been determined.
Target Protein:
FANCD2
Host:
Mouse
Clonality:
Monoclonal
Clone Number:
6
Myeloma:
NS1
Isotype:
IgG
Form:
Liquid
Purity:
Protein G affinity purified.
Purification Note:
From mouse ascitic fluid.
Concentration:
1 mg/ml
Storage Buffer:
Phosphate-buffered saline, pH 7.2, contaning no preservatives
Storage Instruction:
For long term storage, please keep at -70 °C or below. Avoid repeared freeze-thaw cycles.
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