Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||82 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||eukaryotic elongation factor-2 kinase|
|Product Description||Rabbit polyclonal antibody to EEF2K (eukaryotic elongation factor-2 kinase)|
|Background||This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq]|
|Synonyms||HSU93850 antibody, MGC45041 antibody, eEF-2K antibody, EEF2K antibody, eEF-2 kinase antibody, eukaroytic elongation factor 2 kinase antibody, calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase antibody, calmodulin-dependent protein kinase III antibody, eukaryotic elongation factor 2 kinase antibody, calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase antibody, elongation factor-2 kinase antibody, eukaryotic elongation factor-2 kinase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human eEF-2K. The exact sequence is proprietary.|
|Species Reactivity||Human, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (88%), Bovine (89%)|