|Full Name||eukaryotic translation initiation factor 3, subunit B|
|Product Description||Rabbit polyclonal antibody to eIF3 eta (eukaryotic translation initiation factor 3, subunit B)|
|Background||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.|
|Synonyms||EIF3-ETA antibody, EIF3-P110 antibody, EIF3-P116 antibody, EIF3S9 antibody, MGC104664 antibody, MGC131875 antibody, PRT1 antibody, EIF3B antibody, "eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa antibody", prt1 homolog antibody, eukaryotic translation initiation factor 3 subunit 9 antibody, eIF-3-eta antibody, eIF3 p110 antibody, hPrt1 antibody, "eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD) antibody", eIF3 p116 antibody, eukaryotic translation initiation factor 3 subunit B antibody, "eukaryotic translation initiation factor 3, subunit B antibody"|
|Cellular Localization||Cytoplasm |
|Target||eIF3 eta |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human eIF3 eta. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Xenopus laevis, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (99%), Rat (99%), Xenopus laevis (92%), Bovine (99%)|