|Full Name||eukaryotic translation initiation factor 3, subunit C|
|Product Description||Rabbit Polyclonal antibody to eIF3 p110 (eukaryotic translation initiation factor 3, subunit C)|
|Background||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. |
|Synonyms||EIF3CL antibody, EIF3S8 antibody, FLJ53378 antibody, FLJ54400 antibody, FLJ54404 antibody, FLJ55450 antibody, FLJ55750 antibody, FLJ78287 antibody, MGC189737 antibody, MGC189744 antibody, eIF3-p110 antibody, EIF3C antibody, eukaryotic translation initiation factor 3 subunit 8 antibody, eukaryotic translation initiation factor 3 subunit C antibody, cell migration-inducing protein 17 antibody, "eukaryotic translation initiation factor 3, subunit 8 (110kD) antibody", eIF3 p110 antibody, "eukaryotic translation initiation factor 3, subunit 8, 110kDa antibody", "eukaryotic translation initiation factor 3, subunit C antibody"|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human eIF3 p110. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (93%), Xenopus laevis (88%)|